en-US office user

Don't use Application Guard with Office.

Verified with Microsoft 365/Office 5568.1000 — updated on September 4, 2026

Microsoft 365/Office 5568.1000

Supported on: At least Windows Server 2016, Windows 10

Path in the GPO console

User Configuration\Administrative Templates\Microsoft Office 2016\Security Settings\Trust Center\Application Guard

Description

This policy setting allows you to control whether Office apps use Application Guard to isolate untrusted documents. If you enable this policy setting, Office apps won't use Application Guard to isolate untrusted documents even if the device is configured to use Application Guard. Instead, Office will use Protected View to isolate untrusted documents. Note: You should consider enabling this policy setting if you want to stop Office apps from using Application Guard without impacting the use of Application Guard with other applications. If you disable or don't configure this policy settings, Office apps will use Application Guard to isolate untrusted documents. The device must be configured to use Application Guard and the user must be licensed to use Application Guard.

Registry

HKCU software\policies\microsoft\office\16.0\common\security\applicationguard

Value name: disableappguard

Enabled: disableappguard = 1

Disabled: disableappguard = 0

Export Builder

BETA

Configure the state, scope and options, then generate .reg, PowerShell, Intune and SCCM outputs — or add the setting to a multi-setting collection.

These exports write the registry — this is not a managed GPO.

.reg file

Windows Registry Editor Version 5.00

; Exported from gporais.com
; Policy: Don't use Application Guard with Office.
; State: Enabled
; Supported on: At least Windows Server 2016, Windows 10

[HKEY_CURRENT_USER\software\policies\microsoft\office\16.0\common\security\applicationguard]
"disableappguard"=dword:00000001
More formats (PowerShell, Intune, SCCM)

PowerShell

# Exported from gporais.com
# Policy: Don't use Application Guard with Office.
# State: Enabled
# Supported on: At least Windows Server 2016, Windows 10
# Warning: In SYSTEM context (the Intune default), HKCU targets the SYSTEM profile. Run this script using the logged-on credentials.

$path = 'HKCU:\software\policies\microsoft\office\16.0\common\security\applicationguard'
New-Item -Path $path -Force | Out-Null
Set-ItemProperty -Path $path -Name 'disableappguard' -Value 1 -Type DWord

Building a multi-setting collection? Add this setting and generate combined .reg / PowerShell / GPO scripts.

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